THE LABORATORY FOR SCIENCE AND TRANSLATION IN CRITICAL ILLNESS

Because great discoveries come from great collaborations

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Murine PCLS
Murine PCLS

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Lung AngioSense
Lung AngioSense

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Lung TUNEL
Lung TUNEL

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Murine PCLS
Murine PCLS

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Our mission is to promote multidisciplinary science and training among investigators across fields and career stages to drive clinically meaningful advances in our understanding of sepsis and critical illness.

The major focus of this laboratory is to define mechanisms of lung and other organ injury in critical illnesses such as sepsis.

 

We utilize translational methods including primary human cells, animal models, and the ex vivo human lung.

Interested in helping support great science and training?

Come
see us at

Experimental Biology

 

April 2-5, 2022

Philadelphia, PA

Image by Gibson Hurst

Sunday April 3

  • Kaitlyn Schaaf

    • Presentation: Influenza A Virus Causes Shedding of the Alveolar Epithelial Glycocalyx through Activation of Sheddases

    • Session

      • Oral - Transition from Acute to Chronic Critical Illness After Pneumonia: Long-Term Outcomes, End-Organ Dysfunction and Mechanics (9:30-9:45am, Penn. Convention Center, Room 203B)​

      • Poster - APS Lung Biology: Alveolar Epithelial Cell Biology (10:15am-12:15pm, Penn. Convention Center, Exhibit Hall A-B)

  • Jamie Meegan, PhD​​

    • Presentation: Cell-free Hemoglobin-Oxidized LDL Axis Contributes to Microvascular Endothelial Barrier Dysfunction and Poor Outcomes During Sepsis (Poster)

    • Session: APS Permeability/Fluid & Solute Exchange/Glycocalyx, 10:15am-12:15pm, Penn. Convention Center, Exhibit Hall A-B

  • Kyle Riedmann​​

    • Presentation: Cell-free Hemoglobin Increases Leukocyte Adhesion and Mitochondrial Oxidative Damage in the Pulmonary Microvascular Endothelium (Poster)

    • Session: APS Endothelial Cell Biology in Health and Disease, 10:15am-12:15pm, Penn. Convention Center, Exhibit Hall A-B

Monday April 4

  • Brandon Baer, PhD

    • Presentation: Liraglutide as a Prophylactic Treatment for Sepsis Induced Lung Inflammation and Edema (Poster)

    • Session: Drug Discovery and Development, 10am-12pm, Penn. Convention Center, Exhibit Hall A-B

  • Lorraine Ware, MD​​

    • Presentation: Whole Exome Mentoring: Career and Life Mentoring for Junior Faculty (Oral)

    • Session: Next-Generation Sciencing: High Impact Research from Early Career Lung Physiologists, 1:30-2pm, Penn. Convention Center, Room 203A

​​

Tuesday April 5​​

  • Nathan Putz

    • Presentation: Effect of Prolonged Lipopolysaccharide Exposure on Lung Function and Health (Poster)

    • Session: APS Respiratory Physiology, 10:15am-12:15pm, Penn. Convention Center, Exhibit Hall A-B

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